Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651034 | 0.93 | LMNA (0.56) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL13165245 | 0.91 | L3MBTL1 (0.56) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL19647563 | 0.86 | L3MBTL1 (0.46) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL12251342 | 0.84 | L3MBTL1 (0.60) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL21849219 | 0.84 | L3MBTL1 (0.56) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL485746 | 0.84 | SOD1 (0.53) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL10224112 | 0.83 | L3MBTL1 (0.58) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL2089596 | 0.83 | L3MBTL1 (0.57) | L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL12062140 | 0.83 | L3MBTL1 (0.58) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL20267505 | 0.83 | L3MBTL1 (0.58) | L3MBTL1LMNAPOLBHTTSOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590929-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
| US-20120004166-A1 | ARYLOXYALKYLENE-SUBSTITUTED HYDROXYPHENYLHEXYNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-20120004166-A1 | ARYLOXYALKYLENE-SUBSTITUTED HYDROXYPHENYLHEXYNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-20120004166-A1 | ARYLOXYALKYLENE-SUBSTITUTED HYDROXYPHENYLHEXYNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-5242936-A | Phenoxy alkanol esters for treatment of allergic conditions | Berger, Frank M. (US) | 1993-09-07 | — | — | US | disclosed |
| US-5021460-A | P-alkyl phenoxy alkanols for the treatment of allergic conditions | Berger, Frank M. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4816491-A | Treatment of allergic conditions using indanyloxy-alkanol derivatives | Berger, Frank M. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0162975-B1 | P-ALKYL OR CYCLOALKYL PHENOXY ALKANOLS AND ALKANOL ESTERS AND USE FOR THE TREATMENT OF ALLERGIC CONDITIONS | PHARMACO DEVELOPMENT PARTNERS (US) | 1988-07-27 | — | — | EP | disclosed |
| EP-0162975-A1 | P-alkyl or cycloalkyl phenoxy alkanols and alkanol esters and use for the treatment of allergic conditions | PHARMACO DEVELOPMENT PARTNERS (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4543362-A | P-Alkyl or cycloalkyl phenoxy alkanols and alkanol esters and process for the treatment of allergic conditions | Berger, Frank M. (US) | 1985-09-24 | — | — | US | disclosed |
| US-4451474-A | T-Butyl-phenoxy-alkylene esters of benzoic and nicotinic acids, compositions containing same and their antihistaminic method of use | Berger, Frank M. (US) | 1984-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004166-A1 | ARYLOXYALKYLENE-SUBSTITUTED HYDROXYPHENYLHEXYNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT | HCAR1, HCAR3, CYP2C9 | L3MBTL1 4342/4885LMNA 3353/4885POLB 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.