SCHEMBL223528

SCHEMBL223528

Clc1ccc(Br)cc1SSc1cc(Br)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.39
PTPRG P23470 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP2A6 P11509 2/20 0.33
NT5E P21589 1/20 0.32
AHR P35869 2/20 0.32
ALOX15 P16050 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 2/20 0.31
TSHR P16473 1/20 0.31
HSP90AA1 P07900 1/20 0.31
TLR9 Q9NR96 1/20 0.31
S100A4 P26447 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
CYP1A2 P05177 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27818604 0.81 PTPRC (0.37) PTPRCPTPRGALDH1A1CYP2A6NT5E
SCHEMBL2874105 0.81 ALDH1A1 (0.40) PTPRCPTPRGALDH1A1NT5EHPGD
SCHEMBL10624759 0.80 FBP1 (0.38) PTPRCPTPRGALDH1A1CYP2A6NT5E
SCHEMBL224923 0.74 TP53 (0.52) ALDH1A1ALOX15HPGDMAPK1TSHR
SCHEMBL223419 0.74 HSP90AA1 (0.44) PTPRCALDH1A1CYP2A6AHRALOX15
SCHEMBL29405402 0.73
SCHEMBL125688 0.73
SCHEMBL15823851 0.72 PTPRC (0.38) PTPRCPTPRGALDH1A1NT5EMAPT
SCHEMBL20448299 0.71 PTPRC (0.50) PTPRCPTPRGALDH1A1TDP1MAPT
SCHEMBL444906 0.70 AHR (0.48) PTPRCPTPRGALDH1A1CYP2A6AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 918 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-20250018250-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-16 US disclosed
US-20240299812-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-09-12 US disclosed
US-20240269520-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-08-15 US disclosed
US-11712605-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-08-01 US disclosed
US-20230060884-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-03-02 US disclosed
US-20230054484-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-02-23 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 PTPRC 4430/4885PTPRG 4597/4885ALDH1A1 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.