Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPRG | P23470 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714288 | 0.83 | MAPT (0.48) | PTPRCPTPRGKDM4ECYP1A2TDP1 | |
| SCHEMBL4273513 | 0.82 | TDP1 (0.57) | KDM4EPRNPRXFP1CYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL11867344 | 0.81 | TDP1 (0.56) | KDM4EPRNPRXFP1CYP1A2TDP1 | |
| SCHEMBL5423313 | 0.79 | PKM (0.44) | KDM4ECYP1A2TDP1MCL1GRK6 | |
| SCHEMBL29093342 | 0.76 | CYP1A2 (0.46) | KDM4ECYP1A2TDP1MCL1GRK6 | |
| SCHEMBL5506194 | 0.76 | LIG1 (0.47) | KDM4EPRNPRXFP1CYP1A2MCL1 | |
| SCHEMBL11726194 | 0.76 | SMN1; SMN2 (0.51) | PTPRCPTPRGALDH1A1FFAR1GAA | |
| SCHEMBL1157659 | 0.74 | CYP1A2 (0.61) | KDM4ECYP1A2ALDH1A1FFAR1GAA | |
| SCHEMBL29812491 | 0.74 | CYP1A2 (0.61) | KDM4ECYP1A2ALDH1A1FFAR1GAA | |
| SCHEMBL7020250 | 0.73 | ALDH1A1 (0.53) | KDM4ECYP1A2TDP1GRK6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265467-A1 | PYRAZOLIDINE DERIVATIVES AND RELATED COMPOUNDS | SELVITA S.A. (PL) | 2018-09-20 | — | — | US | disclosed |
| EP-3356331-A1 | PYRAZOLIDINE DERIVATIVES AND RELATED COMPOUNDS | Selvita S.A. (PL) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265467-A1 | PYRAZOLIDINE DERIVATIVES AND RELATED COMPOUNDS | LDHB, LDHA, PDK1 | PTPRC 2793/4885PTPRG 2644/4885KDM4E 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.