SCHEMBL223419

SCHEMBL223419

Brc1ccc(Br)c(SSc2cc(Br)ccc2Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
TLR9 Q9NR96 1/20 0.44
ALOX15 P16050 3/20 0.40
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 2/20 0.39
S100A4 P26447 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.38
CYP2A6 P11509 3/20 0.37
AHR P35869 5/20 0.36
PTPRC P08575 1/20 0.33
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX12 P18054 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29661773 0.83 HSP90AA1 (0.44) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL7263834 0.83 HSP90AA1 (0.44) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL1814053 0.78 ALOX15 (0.46) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL15834447 0.74 ALDH1A1 (0.38) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL5594958 0.74 NPC1 (0.47) ALOX15MAPK1ALDH1A1TDP1MEN1
SCHEMBL7262565 0.74 POLB (0.47) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL223528 0.74 PTPRC (0.39) HSP90AA1TLR9ALOX15MAPK1ALDH1A1
SCHEMBL9630967 0.69 MAPK1 (0.48) ALOX15MAPK1ALDH1A1TSHRMEN1
SCHEMBL10540076 0.69 NR1H2 (0.48) HSP90AA1TLR9ALOX15S100A4SMN1; SMN2
SCHEMBL16324994 0.69 POLB (0.34) HSP90AA1TLR9ALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
US-20260027422-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-29 US disclosed
US-20250269241-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-08-28 US disclosed
US-12357881-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-07-15 US disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
US-6241625-B1 A GOLF BALL COMPRISING A COVER MEMBER AND A CORE MEMBER, WHEREIN POLYAMIDE, TERPOLYMER IONOMER CONTAINING ETHYLENE, (METH)ACRYLIC ACID, AND (METH)ACRYLIC ESTER MIXTURES WITH PEROXIDE AND SULFIDE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-06-05 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027422-A1 GOLF BALL KIF5A, KIF5C, SURF4 HSP90AA1 274/4885TLR9 1961/4885ALOX15 3000/4885
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 HSP90AA1 229/4885TLR9 1553/4885ALOX15 3009/4885
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 HSP90AA1 5/4885TLR9 2909/4885ALOX15 3014/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 HSP90AA1 1384/4885TLR9 1526/4885ALOX15 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.