Methacrylic Acid

Methacrylic Acid

SCHEMBL2236061

C=C(C)C(=O)O.C=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)c(OCC)c2OCC)c(OCC)c1OCC

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HSD17B10 Q99714 1/20 0.34
ELANE P08246 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 3/20 0.31
CREBBP Q92793 1/20 0.31
RXRA P19793 3/20 0.31
RARG P13631 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5604507 1.00 ALDH1A1 (0.34) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL29415623 0.96 CYP1A2 (0.35) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL64707 0.96 CYP1A2 (0.35) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL6479131 0.90 CYP2C9 (0.32) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL9065029 0.88 ALDH1A1 (0.38) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
Methacrylic Acid SCHEMBL9099472 0.88 THRB (0.35) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL6295108 0.87 CYP1A2 (0.32) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL29771136 0.87 TSHR (0.35) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL66400 0.87 TSHR (0.35) ALDH1A1HPGDL3MBTL1KDM4EHSD17B10
SCHEMBL11214664 0.87 VDR (0.31) CYP1A2CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61211386-A None JP disclosed
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed
WO-2007037501-A9 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON CATALYTIC CHEM IND (JP) 2007-05-24 WO disclosed
JP-S61211386-A ANAEROBICALLY CURABLE COMPOSITION HAVING EXCELLENT STABILITY SURIIBONDO:KK 1986-09-19 JP disclosed