Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20915137 | 0.84 | PGR (0.59) | SLC6A4PGRNR3C1ADORA3SLC6A2 | |
| SCHEMBL5173777 | 0.77 | NR1I2 (0.62) | NR1I2PDK1PDK2PDK3PDK4 | |
| SCHEMBL5173779 | 0.77 | NR1I2 (0.62) | NR1I2PDK1PDK2PDK3PDK4 | |
| Norelgestromin SCHEMBL4814611 | 0.76 | NR1I2 (1.00) | NR1I2PDK1PDK2PDK3PDK4 | |
| Norelgestromin SCHEMBL118611 | 0.76 | NR1I2 (1.00) | NR1I2PDK1PDK2PDK3PDK4 | |
| Norelgestromin SCHEMBL3267125 | 0.76 | NR1I2 (1.00) | NR1I2PDK1PDK2PDK3PDK4 | |
| Norelgestromin SCHEMBL3163347 | 0.76 | NR1I2 (1.00) | NR1I2PDK1PDK2PDK3PDK4 | |
| Norelgestromin SCHEMBL4814600 | 0.76 | NR1I2 (1.00) | NR1I2PDK1PDK2PDK3PDK4 | |
| SCHEMBL13306245 | 0.76 | NR1I2 (0.78) | NR1I2PDK1PDK2PDK3PDK4 | |
| SCHEMBL28485021 | 0.74 | PDK1 (0.58) | NR1I2PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10758478-B2 | Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same | LABORATORY SKIN CARE, INC. (US) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758478-B2 | Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same | CHERP, ORAI1, CA2 | NR1I2 4250/4885PDK1 2759/4885PDK2 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.