Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321471 | 0.90 | STS (0.39) | OPRD1OPRK1STSMAPK1GPR119 | |
| SCHEMBL24596421 | 0.81 | — | — | |
| SCHEMBL22147583 | 0.80 | MAPK1 (0.40) | OPRD1OPRK1STSMAPK1GPR119 | |
| SCHEMBL22148053 | 0.78 | HCRTR2 (0.33) | MEN1KMT2AKDM4E | |
| SCHEMBL27573516 | 0.76 | L3MBTL1 (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4394294 | 0.74 | CTSK (0.31) | — | |
| SCHEMBL3788943 | 0.73 | — | — | |
| SCHEMBL25414924 | 0.72 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL5174281 | 0.72 | SIGMAR1 (0.40) | OPRD1OPRK1STSMAPK1MEN1 | |
| SCHEMBL7345681 | 0.72 | SMN1; SMN2 (0.40) | OPRD1OPRK1STSGPR119ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699173-A1 | GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME | California Institute of Technology (US) | 2020-08-26 | — | — | EP | disclosed |