Sugi Predict

Sugi Predict / Compounds / Methane

Methane

Methane

SCHEMBL22366555

C.NC1(N)CC=CC=C1c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PNMT P11086 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL734441 0.98 PNMT (0.32) PNMTMAOAMAOB
SCHEMBL28815366 0.79 CYP3A4 (0.31) PNMTMAOAMAOB
SCHEMBL30587795 0.79 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL29385662 0.79 SLC6A2 (0.32) PNMTMAOAMAOB
SCHEMBL9537410 0.79 MAOB (0.32) PNMTMAOAMAOB
SCHEMBL28872725 0.79 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL1153470 0.79 MAOA (0.33) PNMTMAOAMAOB
SCHEMBL22129387 0.79 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL2873957 0.79 HNF4A (0.33) —
SCHEMBL31442063 0.78 PNMT (0.37) PNMTMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114380714-B Circulating solvent in phosgenation production and impurity removing method thereof 万华化学集团股份有限公司 2023-08-11 — — CN claimed
EP-3700922-A1 VESICLE INCORPORATING TRANSMEMBRANE PROTEIN Aquaporin A/S (DK) 2020-09-02 — — EP disclosed
CN-107250902-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal represent element 日产化学工业株式会社 2017-10-13 — — CN disclosed