SCHEMBL30587795

SCHEMBL30587795

NC1([Pd+2])CC=CC=C1c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL734441 0.81 PNMT (0.32) PNMTMAOAMAOB
Methane SCHEMBL22366555 0.79 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL29385662 0.78 SLC6A2 (0.32) PNMTMAOAMAOB
SCHEMBL9537410 0.78 MAOB (0.32) PNMTMAOAMAOB
SCHEMBL28815366 0.78 CYP3A4 (0.31) PNMTMAOAMAOB
SCHEMBL28872725 0.78 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL1153470 0.78 MAOA (0.33) PNMTMAOAMAOB
SCHEMBL22129387 0.78 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL3992253 0.77 ALDH1A1 (0.31)
SCHEMBL31442063 0.76 PNMT (0.37) PNMTMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836157-A Oxadiazole derivative and preparation method and application thereof 星希尔生物科技(上海)有限公司 2023-10-03 CN disclosed
WO-2023179366-A1 OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 星希尔生物科技(上海)有限公司 2023-09-28 WO disclosed