SCHEMBL734441

SCHEMBL734441

NC1(N)CC=CC=C1c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL22366555 0.98 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL28815366 0.81 CYP3A4 (0.31) PNMTMAOAMAOB
SCHEMBL29385662 0.81 SLC6A2 (0.32) PNMTMAOAMAOBSLC6A2SLC6A4
SCHEMBL30587795 0.81 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL9537410 0.81 MAOB (0.32) PNMTMAOAMAOB
SCHEMBL28872725 0.81 PNMT (0.31) PNMTMAOAMAOB
SCHEMBL1153470 0.81 MAOA (0.33) PNMTMAOAMAOBSLC6A2SLC6A4
SCHEMBL22129387 0.81 PNMT (0.31) PNMTMAOAMAOBSLC6A2SLC6A4
SCHEMBL2873957 0.80 HNF4A (0.33) ALDH1A1
SCHEMBL31442063 0.79 PNMT (0.37) PNMTMAOAMAOBSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119191989-A Reduction process of 2, 2-dinitrobibenzyl 浙江华洲药业有限公司 2024-12-27 CN disclosed
CN-119191989-A Reduction process of 2, 2-dinitrobibenzyl 浙江华洲药业有限公司 2024-12-27 CN disclosed
CN-115948022-A Prepreg, circuit board and printed circuit board 浙江华正新材料股份有限公司 2023-04-11 CN disclosed
EP-3515898-B1 PROCESS FOR THE PREPARATION OF POLYAMINES STARTING FROM DINITRILES AND/OR AMINONITRILES BASF SE (DE) 2020-11-11 EP disclosed
EP-3029041-B1 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORP (US) 2020-03-04 EP disclosed
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2020-02-27 US disclosed
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta ICOS CORPORATION (US) 2019-09-03 US disclosed
EP-3515898-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2019-07-31 EP disclosed
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2019-07-18 US disclosed
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA ICOS CORPORATION 2018-12-20 US disclosed
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives ICOS CORPORATION, A DELAWARE CORPORATION 2002-10-31 US disclosed
WO-2001081346-A2 INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA ICOS CORPORATION (US) 2001-11-01 WO disclosed
US-5347019-A REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES CASSELLA AG (DE) 1994-09-13 US disclosed
EP-0270665-A4 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM. AMERON INC (US) 1988-09-28 EP disclosed
EP-0270665-A1 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM AMERON, INC. (US) 1988-06-15 EP disclosed
WO-1987007287-A1 SOLVENTLESS POLYURETHANE SPRAY COMPOSITIONS AND METHOD FOR APPLYING THEM AMERON, INC. (US) 1987-12-03 WO disclosed
US-4695618-A Solventless polyurethane spray compositions and method for applying them AMERON, INC. (US) 1987-09-22 US disclosed
US-4369318-A USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST CIBA-GEIGY LTD. (CH) 1983-01-18 US disclosed
US-4266011-A FUSED PYRIDAZINE CATALYST CIBA-GEIGY AG (CH) 1981-05-05 US disclosed
US-4008254-A Ceria catalyzed conversion of phenols to dibenzofurans in the presence of water vapor MONSANTO COMPANY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360832-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PNMT 3904/4885MAOA 4472/4885MAOB 4415/4885
US-20020161014-A1 Purinyl substituted quinazoline-4-one derivatives PIK3CD, PIK3CA, PIK3CG PNMT 1465/4885MAOA 3760/4885MAOB 4002/4885
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES SRM, PRMT1, HNMT PNMT 4/4885MAOA 217/4885MAOB 202/4885
US-20200061062-A1 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA PIK3CD, PIK3CA, PIK3CG PNMT 3904/4885MAOA 4472/4885MAOB 4415/4885
US-10398695-B2 Inhibitors of human phosphatidylinositol 3-kinase delta PIK3CD, PIK3CA, PIK3CG PNMT 3904/4885MAOA 4472/4885MAOB 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.