SCHEMBL2237236

SCHEMBL2237236

c1csc(-c2ccc(-c3cccs3)c3nccnc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.47
CYP2E1 P05181 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2B6 P20813 1/20 0.44
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CDK5 Q00535 3/20 0.43
CDK5R1 Q15078 2/20 0.43
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CCNB1 P14635 1/20 0.43
GSK3B P49841 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28083058 0.91 TOP2A (0.49) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL12949721 0.86 GLO1 (0.42) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL27863584 0.83 CDK5 (0.45) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL20837416 0.80 CYP3A4 (0.45) CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6
SCHEMBL6666438 0.79 KDM4E (0.52) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL41299 0.78 KDM4E (0.43) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL3358739 0.78 TOP2A (0.59) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL28335119 0.77 KDM4E (0.50) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
Hydrochloric Acid SCHEMBL6667707 0.77 KDM4E (0.50) GLO1CYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL28132260 0.77 KDM4E (0.50) GLO1CYP2E1CYP3A4CYP2A6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119092306-A Quinoxaline-based polymer electrochromic electrode material, and preparation method and application thereof 华南理工大学 2024-12-06 CN claimed
CN-107353301-B Boron-nitrogen-mixed aromatic compound and synthesis method and application thereof 天津理工大学 2020-04-14 CN claimed
EP-2536700-B1 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2019-10-02 EP claimed
US-9365585-B2 Semiconducting polymers MERCK PATENT GMBH (DE) 2016-06-14 US claimed
US-9212260-B2 Polymers of 8,9-dihydrobenzo[def]carbazole and their use as organic semiconductors MERCK PATENT GMBH (DE) 2015-12-15 US claimed
EP-2631230-B1 Semiconducting Polymers MERCK PATENT GMBH (DE) 2015-01-21 EP claimed
EP-2563836-B1 POLYMERS OF 8,9-DIHYDROBENZO(DEF)CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2014-03-26 EP claimed
EP-2631230-A1 Semiconducting Polymers Merck Patent GmbH (DE) 2013-08-28 EP claimed
EP-2563836-A1 POLYMERS OF 8,9-DIHYDROBENZO(DEF)CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2013-03-06 EP claimed
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-01-03 US claimed
EP-2536700-A2 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2012-12-26 EP claimed
US-20120305853-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 US claimed
WO-2011116866-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-09-29 WO claimed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 WO claimed
CN-119092306-A Quinoxaline-based polymer electrochromic electrode material, and preparation method and application thereof 华南理工大学 2024-12-06 CN disclosed
CN-107353301-B Boron-nitrogen-mixed aromatic compound and synthesis method and application thereof 天津理工大学 2020-04-14 CN disclosed
EP-2536700-B1 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2019-10-02 EP disclosed
US-20110272030-A1 MATERIAL FOR PHOTOVOLTAIC DEVICE, AND PHOTOVOLTAIC DEVICE TORAY INDUSTRIES, INC. (JP) 2011-11-10 US disclosed
WO-2011116866-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-09-29 WO disclosed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS DDT, PPOX, DDO GLO1 1102/4885CYP2E1 562/4885CYP3A4 535/4885
US-20120305853-A1 SEMICONDUCTING POLYMERS PPOX, OCIAD2, OCIAD1 GLO1 759/4885CYP2E1 1958/4885CYP3A4 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.