Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31621718 | 0.80 | HTT (0.66) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9180978 | 0.80 | HTT (0.66) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11030583 | 0.78 | HTT (0.77) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8712114 | 0.78 | HTT (0.68) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL22372356 | 0.77 | ALDH1A1 (0.45) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL18796141 | 0.77 | HTT (1.00) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18796180 | 0.77 | HTT (0.66) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18796190 | 0.77 | HTT (0.66) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6827514 | 0.75 | KDM4E (0.51) | MEN1KMT2AKDM4E | |
| SCHEMBL22372364 | 0.74 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200275656-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200275656-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | PIK3C3, DDT, ERG28 | HTT 3997/4885ALDH1A1 3077/4885MEN1 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.