Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372361 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL24287258 | 0.78 | ALDH1A1 (0.50) | L3MBTL1TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL18796404 | 0.75 | LCK (0.52) | L3MBTL1TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL16795314 | 0.75 | ALDH1A1 (0.54) | L3MBTL1TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL18796088 | 0.75 | L3MBTL1 (0.47) | L3MBTL1TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL22372363 | 0.74 | HTT (0.62) | L3MBTL1KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL5950358 | 0.74 | SLC6A2 (0.50) | TSHRKDM4ESLC6A2SLC6A4 | |
| SCHEMBL24287256 | 0.72 | L3MBTL1 (0.45) | L3MBTL1TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL11401433 | 0.72 | L3MBTL1 (0.74) | L3MBTL1TSHRKDM4EPOLBHPGD | |
| SCHEMBL5720727 | 0.71 | TSHR (0.70) | L3MBTL1TSHRKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200275656-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200275656-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | PIK3C3, DDT, ERG28 | L3MBTL1 1675/4885TSHR 4507/4885KDM4E 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.