Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19450704 | 0.95 | CAPN1 (0.37) | CAPN1GLO1BCHEACHENOD1 | |
| SCHEMBL20998090 | 0.85 | CAPN1 (0.33) | CAPN1GLO1BCHEACHENOD1 | |
| SCHEMBL19505993 | 0.84 | CAPN1 (0.33) | CAPN1GLO1BCHEACHENOD1 | |
| SCHEMBL19506154 | 0.78 | CTSS (0.37) | CAPN1GLO1NOD1CTSSCTSK | |
| SCHEMBL30019872 | 0.77 | NOD1 (0.47) | CAPN1NOD1 | |
| SCHEMBL20998108 | 0.77 | CTSK (0.41) | CAPN1GLO1CTSLCTSBNOD1 | |
| SCHEMBL25977123 | 0.77 | CAPN1 (0.43) | CAPN1NMT2NMT1BCHEACHE | |
| SCHEMBL30019912 | 0.77 | NOD1 (0.47) | CAPN1NOD1 | |
| SCHEMBL24235778 | 0.75 | GLP1R (0.43) | CAPN1NMT2NMT1NOD1 | |
| SCHEMBL20380968 | 0.74 | ALDH1A1 (0.44) | CAPN1LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268885-A1 | Conjugates And Conjugating Reagents | POLYTHERICS LIMITED (GB) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268885-A1 | Conjugates And Conjugating Reagents | ANPEP, NGLY1, PCTP | CAPN1 2310/4885NMT2 532/4885NMT1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.