Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374866 | 0.87 | TDP1 (0.37) | ALDH1A1POLBSMN1; SMN2BDKRB1CYP2C19 | |
| SCHEMBL22374861 | 0.78 | BDKRB1 (0.35) | ALDH1A1POLBSMN1; SMN2BDKRB1CYP2C19 | |
| SCHEMBL26445138 | 0.77 | L3MBTL1 (0.45) | ALDH1A1POLBBDKRB1TDP1L3MBTL1 | |
| SCHEMBL26445170 | 0.77 | L3MBTL1 (0.45) | ALDH1A1POLBBDKRB1TDP1L3MBTL1 | |
| SCHEMBL23729306 | 0.72 | HTR7 (0.39) | ALDH1A1SMN1; SMN2TP53CYP2C19TSHR | |
| SCHEMBL4569286 | 0.72 | PIK3CD (0.55) | ALDH1A1SMN1; SMN2TP53CYP2C19TDP1 | |
| SCHEMBL24674880 | 0.71 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2CYP2C19TDP1 | |
| SCHEMBL24712849 | 0.71 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2TP53CYP2C19 | |
| SCHEMBL22374865 | 0.69 | PIK3CD (0.49) | ALDH1A1POLBCYP2C19L3MBTL1TSHR | |
| SCHEMBL29299601 | 0.69 | HTR7 (0.41) | ALDH1A1SMN1; SMN2TP53TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | ALDH1A1 3756/4885POLB 2253/4885SMN1; SMN2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.