Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 12/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254206 | 0.83 | NOS1 (0.50) | NOS1NOS3NOS2 | |
| SCHEMBL7046423 | 0.77 | NOS1 (0.56) | NOS1NOS3NOS2 | |
| SCHEMBL23023820 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL22511690 | 0.74 | NOS1 (0.65) | NOS1NOS3NOS2 | |
| SCHEMBL19405238 | 0.73 | NOS1 (0.48) | NOS1NOS3NOS2 | |
| SCHEMBL20475545 | 0.73 | BACE1 (0.52) | NOS1NOS3NOS2 | |
| SCHEMBL22521588 | 0.72 | NOS1 (0.50) | NOS1NOS2 | |
| SCHEMBL24929052 | 0.72 | CPB2 (0.46) | NOS1NOS3NOS2 | |
| SCHEMBL23330365 | 0.71 | BACE1 (0.53) | NOS1NOS2 | |
| SCHEMBL11809448 | 0.70 | NOS3 (0.58) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759791-B2 | Mammalian and bacterial nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759791-B2 | Mammalian and bacterial nitric oxide synthase inhibitors | NOS1, NOS2, NOS3 | NOS1 1/4885NOS3 3/4885NOS2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.