Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449032 | 0.90 | TP53 (0.38) | CAPN1NPC1RAB9ARXFP1CASP1 | |
| SCHEMBL28547699 | 0.86 | CASP1 (0.38) | CAPN1NPC1RAB9ACASP3CASP1 | |
| SCHEMBL22167272 | 0.85 | CTSB (0.35) | NPC1RAB9ARXFP1MMEHDAC1 | |
| SCHEMBL15019919 | 0.85 | MME (0.42) | MMEHPGDS | |
| SCHEMBL15019922 | 0.85 | MME (0.42) | MMEHPGDS | |
| SCHEMBL22384071 | 0.84 | RARB (0.39) | NPC1RAB9A | |
| SCHEMBL17825497 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL17825520 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL15037038 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL17459640 | 0.81 | MME (0.41) | MMEHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |