Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384192 | 0.86 | CAPN1 (0.36) | CASP1NPC1RAB9ACAPN1CASP3 | |
| SCHEMBL17459539 | 0.85 | ITGA4 (0.42) | NPC1KMT2A | |
| SCHEMBL17459538 | 0.85 | ITGA4 (0.42) | NPC1KMT2A | |
| SCHEMBL17468458 | 0.81 | MAPT (0.42) | KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL17459574 | 0.78 | PYGL (0.38) | NPC1RAB9ASMYD3SMN1; SMN2HPGD | |
| SCHEMBL17459576 | 0.78 | PYGL (0.38) | NPC1RAB9ASMYD3SMN1; SMN2HPGD | |
| SCHEMBL22167459 | 0.78 | SMYD3 (0.33) | CASP1NPC1RAB9ASMYD3SMN1; SMN2 | |
| SCHEMBL22449032 | 0.76 | TP53 (0.38) | CASP1NPC1KMT2ARAB9ACAPN1 | |
| SCHEMBL17459575 | 0.76 | SMYD3 (0.34) | NPC1KMT2ARAB9ASMYD3SMN1; SMN2 | |
| SCHEMBL22167308 | 0.74 | FPR2 (0.34) | NPC1KMT2ARAB9ASMYD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |