Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375225 | 0.90 | CTSS (0.42) | PSMB5PSMB1PSMB8PSMB9BCHE | |
| SCHEMBL22384200 | 0.90 | CTSS (0.42) | PSMB5PSMB1PSMB8PSMB9BCHE | |
| SCHEMBL22756206 | 0.85 | RARB (0.42) | PSMB5ITGB3ITGA2BCTSSCTSK | |
| SCHEMBL22384114 | 0.83 | CTSS (0.44) | CTSSCTSKBCL2 | |
| SCHEMBL16294799 | 0.81 | CTSS (0.45) | CTSSCTSK | |
| SCHEMBL16294798 | 0.81 | CTSS (0.45) | CTSSCTSK | |
| SCHEMBL22756131 | 0.80 | CTSS (0.42) | PSMB5CTSSCTSKBCL2 | |
| SCHEMBL16306026 | 0.79 | CTSS (0.37) | PSMB5PSMB1PSMB8PSMB9ACACB | |
| SCHEMBL16305975 | 0.77 | CTSS (0.40) | ACACBITGB3ITGA2BCTSS | |
| SCHEMBL22384055 | 0.76 | L3MBTL1 (0.42) | PSMB5ITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |