Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834646 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834684 | 0.90 | GPR132 (0.41) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834624 | 0.90 | L3MBTL1 (0.41) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834635 | 0.90 | ITGB1 (0.40) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834669 | 0.89 | DGAT1 (0.41) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834638 | 0.89 | ITGB1 (0.40) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL17834643 | 0.89 | ITGB1 (0.40) | ITGB3ITGA2BGPR132ITGB1ITGA5 | |
| SCHEMBL19481403 | 0.89 | GPR132 (0.46) | ITGB3ITGA2BGPR132ITGB1ITGA4 | |
| SCHEMBL17995135 | 0.88 | CA2 (0.46) | GPR132ITGB1ITGA4CA2 | |
| SCHEMBL17834647 | 0.88 | ITGB1 (0.40) | ITGB3ITGA2BGPR132ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |