Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036211 | 0.92 | MEN1 (0.47) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL10340685 | 0.85 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL5201000 | 0.85 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL11700396 | 0.83 | LMNA (0.61) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL16074981 | 0.83 | MEN1 (0.58) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL9717110 | 0.82 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL13057738 | 0.82 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL12999684 | 0.82 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL14047326 | 0.82 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL7034495 | 0.82 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952025-B2 | Multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-10 | — | — | US | claimed |
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari (US) | 2013-10-10 | — | — | US | claimed |
| EP-2536690-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | Arizona Board Of Regents (US) | 2012-12-26 | — | — | EP | claimed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | claimed |
| CN-1543664-A | Silicone resins and porous materials produced therefrom | — | 2004-11-03 | — | — | CN | claimed |
| EP-1425781-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | Dow Corning Corporation (US) | 2004-06-09 | — | — | EP | claimed |
| US-6737117-B2 | LOW DIELECTRIC CONSTANT, LOW SIH CONTENT, AND RELATIVELY HIGH MODULUS SILICA COATINGS; POLYSILSESQUIOXANE AND A RESIN OF THE FORMULA HSIO3/2 | DOW CORNING CORPORATION | 2004-05-18 | — | — | US | claimed |
| US-20030191267-A1 | Hydrosilsesquioxane resin compositions having improved thin film properties | DOW CORNING CORPORATION | 2003-10-09 | — | — | US | claimed |
| US-6596834-B2 | Silicone resins having the general formula (R1SiO3/2)x(HSiO3/2)y where R1 is an alkyl group having 8 to 24 carbon atoms; x has a value of 0.05 to 0.7; y has a value of 0.3 to 0.95 and x+y =1. The resins are used to form porous | DOW CORNING CORPORATION | 2003-07-22 | — | — | US | claimed |
| US-20030088016-A1 | Silicone resins and porous materials produced therefrom | DOW CORNING CORPORATION | 2003-05-08 | — | — | US | claimed |
| WO-2003023831-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | DOW CORNING CORPORATION (US) | 2003-03-20 | — | — | WO | claimed |
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |
| US-8952025-B2 | Multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari (US) | 2013-10-10 | — | — | US | disclosed |
| CN-100361280-C | Plasma curing method of porous low-dielectric constant material | AXCELIS TECH INC (US) | 2008-01-09 | — | — | CN | disclosed |
| US-6596834-B2 | Silicone resins having the general formula (R1SiO3/2)x(HSiO3/2)y where R1 is an alkyl group having 8 to 24 carbon atoms; x has a value of 0.05 to 0.7; y has a value of 0.3 to 0.95 and x+y =1. The resins are used to form porous | DOW CORNING CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20030088016-A1 | Silicone resins and porous materials produced therefrom | DOW CORNING CORPORATION | 2003-05-08 | — | — | US | disclosed |
| US-20030054115-A1 | Ultraviolet curing process for porous low-K materials | AXCELIS TECHNOLOGIES, INC. | 2003-03-20 | — | — | US | disclosed |
| WO-2003023831-A1 | SILICONE RESINS AND POROUS MATERIALS PRODUCED THEREFROM | DOW CORNING CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |
| US-20020106500-A1 | Plasma curing process for porous low-k materials | SILICON VALLEY BANK | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | SQOR, GSR, GPX4 | MEN1 3951/4885CYP3A4 452/4885ALOX15 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.