Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | HTR2B | P41595 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20942315 | 0.93 | ENPP2 (0.43) | ENPP2DPP4F2F10HPN | |
| Trifluoroacetic Acid SCHEMBL31655669 | 0.89 | F10 (0.39) | SLC2A1DPP4F2F10HPN | |
| Trifluoroacetic Acid SCHEMBL22390335 | 0.85 | F2 (0.39) | F2F10HTR2CHTR2BHTR2A | |
| SCHEMBL22390478 | 0.85 | SCN9A (0.34) | DPP4F2F10HPNPRSS1 | |
| SCHEMBL17062837 | 0.82 | F10 (0.42) | DPP4F2F10HPNPRSS1 | |
| SCHEMBL29516262 | 0.80 | SIGMAR1 (0.47) | F2F10HPNPRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL31655667 | 0.80 | ITGB3 (0.36) | HTR2CHTR2BHTR2ASCN9A | |
| SCHEMBL20616288 | 0.79 | F10 (0.40) | ENPP2F2F10HPNPRSS1 | |
| SCHEMBL20616290 | 0.79 | F10 (0.40) | ENPP2F2F10HPNPRSS1 | |
| Hydrochloric Acid SCHEMBL3602646 | 0.79 | SIGMAR1 (0.46) | F2F10HPNPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261190-B2 | Dihydropyrimidine compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-03-01 | — | — | US | disclosed |
| US-20200283445-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283445-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | TPMT, DPYD, SLC10A1 | ENPP2 3137/4885SLC2A1 854/4885DPP4 166/4885 |
| US-11261190-B2 | Dihydropyrimidine compounds and uses thereof in medicine | DPYD, TPMT, SLC10A1 | ENPP2 3033/4885SLC2A1 921/4885DPP4 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.