Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | HPN | P05981 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20616290 | 1.00 | F10 (0.40) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL17062837 | 0.96 | F10 (0.42) | F10HPNPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL31655669 | 0.90 | F10 (0.39) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL20942315 | 0.85 | ENPP2 (0.43) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL29516262 | 0.83 | SIGMAR1 (0.47) | F10HPNPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL3602646 | 0.82 | SIGMAR1 (0.46) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL20615885 | 0.80 | ALDH1A1 (0.42) | F10HPNPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL22390477 | 0.79 | ENPP2 (0.39) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL20615914 | 0.78 | HTR2C (0.37) | HTR2AHTR2CHTR2BMMP13 | |
| SCHEMBL20615913 | 0.78 | HTR2C (0.37) | HTR2AHTR2CHTR2BMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019001396-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-01-03 | — | — | WO | disclosed |