Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239611 | 0.86 | HPGD (0.64) | ALDH1A1SMN1; SMN2PTPN1MEN1KMT2A | |
| SCHEMBL21669919 | 0.84 | ULK1 (0.56) | SMN1; SMN2MGLLMEN1KMT2AHPGD | |
| SCHEMBL21669936 | 0.84 | ULK1 (0.56) | SMN1; SMN2MGLLMEN1KMT2AHPGD | |
| SCHEMBL21670359 | 0.84 | HDAC3 (0.51) | ALDH1A1SMN1; SMN2MGLLMEN1KMT2A | |
| SCHEMBL21669844 | 0.84 | HDAC3 (0.51) | ALDH1A1SMN1; SMN2MGLLMEN1KMT2A | |
| SCHEMBL21670360 | 0.84 | HDAC3 (0.51) | ALDH1A1SMN1; SMN2MGLLMEN1KMT2A | |
| SCHEMBL30976769 | 0.82 | HPGD (0.58) | ALDH1A1SMN1; SMN2PTPN1MEN1KMT2A | |
| SCHEMBL4096062 | 0.82 | PTPN1 (0.58) | ALDH1A1SMN1; SMN2PTPN1MEN1KMT2A | |
| SCHEMBL21670326 | 0.82 | MGLL (0.52) | SMN1; SMN2MGLLMEN1KMT2AHPGD | |
| SCHEMBL21670580 | 0.82 | KMT2A (0.54) | SMN1; SMN2MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | NAT1, NHERF1, ADORA1 | ALDH1A1 507/4885SMN1; SMN2 3065/4885PTPN1 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.