SCHEMBL2239650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2242413	0.84	PDGFRB (0.45)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL2239932	0.84	PDGFRB (0.45)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL12353596	0.84	PDGFRB (0.51)	TDP1PDGFRBFGFR1PDGFRAFLT1
	SCHEMBL32659719	0.84	PDGFRB (0.51)	TDP1PDGFRBFGFR1PDGFRAFLT1
	SCHEMBL2425959	0.83	CFTR (0.51)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL27386925	0.83	TDP1 (0.47)	TDP1PDGFRBFGFR1PDGFRAFLT1
	SCHEMBL13088964	0.83	TRPA1 (0.47)	MAPTMEN1KMT2ASMN1; SMN2KDM4E
	SCHEMBL2243130	0.82	TDP1 (0.46)	TDP1MAPTMEN1KMT2ASMN1; SMN2
	SCHEMBL23970914	0.82	PDGFRB (0.43)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL1786813	0.82	MEN1 (0.51)	TDP1PDGFRBFGFR1PDGFRAFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.