Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | ALPI | P09923 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.65 |
| ▸ | ALPL | P05186 | 2/20 | 0.60 |
| ▸ | ALPG | P10696 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402477 | 0.84 | KDM4E (1.00) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL31436253 | 0.84 | KDM4E (1.00) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL26034914 | 0.84 | KDM4E (1.00) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL6503931 | 0.81 | POLB (0.62) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL19736057 | 0.80 | CYP19A1 (0.62) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL382208 | 0.80 | CYP19A1 (0.62) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL17559164 | 0.80 | CYP19A1 (0.65) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL15453089 | 0.79 | MAPT (0.75) | KDM4EPOLBALPIGAAMAPT | |
| SCHEMBL30335258 | 0.79 | CYP19A1 (1.00) | CYP19A1PTPN1CYP3A4 | |
| SCHEMBL31139349 | 0.77 | CYP19A1 (0.71) | KDM4EPOLBALPIGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210196607-A1 | COMPOSITION FOR IMPROVING SKIN WHITENING OR AMELIORATING THERMAL SKIN AGING COMPRISING 8-METHOXYBUTIN | Hesed Bio Co., Ltd. (KR) | 2021-07-01 | — | — | US | disclosed |
| US-20210196607-A1 | COMPOSITION FOR IMPROVING SKIN WHITENING OR AMELIORATING THERMAL SKIN AGING COMPRISING 8-METHOXYBUTIN | Hesed Bio Co., Ltd. (KR) | 2021-07-01 | — | — | US | disclosed |
| EP-3705110-A1 | COMPOSITION FOR IMPROVING SKIN WHITENING OR AMELIORATING THERMAL SKIN AGING COMPRISING 8-METHOXYBUTIN | Hesed Bio Co., Ltd. (KR) | 2020-09-09 | — | — | EP | disclosed |
| CN-111372560-A | Composition comprising 8-methoxy fisetin for improving skin lightening or improving skin heat aging | 赫赛德生物有限公司 | 2020-07-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196607-A1 | COMPOSITION FOR IMPROVING SKIN WHITENING OR AMELIORATING THERMAL SKIN AGING COMPRISING 8-METHOXYBUTIN | TYR, HSPB1, HSPA8 | KDM4E 1155/4885POLB 151/4885ALPI 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.