SCHEMBL2240147

SCHEMBL2240147

O=[N+]([O-])c1ccc(-n2cccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 1/20 0.56
ALDH1A1 P00352 4/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.49
SIRT6 Q8N6T7 2/20 0.47
POLB P06746 2/20 0.47
ADRB1 P08588 1/20 0.47
ACHE P22303 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
PLEC Q15149 1/20 0.45
CRHBP P24387 1/20 0.44
ATM Q13315 1/20 0.44
CRHR2 Q13324 1/20 0.44
TLR9 Q9NR96 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123299 0.94 SCN2A (0.51) SCN2AALDH1A1MAPTLMNAHTT
SCHEMBL20238568 0.89 HSPB1 (0.56) SCN2AALDH1A1MAPTLMNAHTT
SCHEMBL85590 0.83 ALDH1A1 (0.49) SCN2AALDH1A1MAPTLMNAHTT
SCHEMBL6140974 0.78 CYP19A1 (0.50) SCN2AALDH1A1MAPTLMNAPOLB
SCHEMBL2650646 0.78 SCN2A (0.60) SCN2AALDH1A1MAPTLMNAPOLB
SCHEMBL12841489 0.77 MEN1 (0.50) SCN2AALDH1A1MAPTHTTSIRT6
SCHEMBL85578 0.76 SCN2A (0.54) SCN2AALDH1A1MAPTLMNAHTT
Benzene SCHEMBL28311584 0.75 ALDH1A1 (0.82) ALDH1A1LMNAPOLBACHEHSD17B10
SCHEMBL22567 0.75 ALDH1A1 (0.72) ALDH1A1LMNAACHEHSD17B10MEN1
SCHEMBL27909482 0.75 ALDH1A1 (0.72) ALDH1A1LMNAACHEHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105336-B Viologen derivative electrochromic material and preparation method thereof 华南理工大学 2020-09-22 CN claimed
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US claimed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US claimed
EP-2135313-B1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP claimed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
EP-2135313-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M Innovative Properties Company (US) 2009-12-23 EP claimed
WO-2008127828-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-23 WO claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
US-4585581-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-4488943-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity and methods for manufacturing such blends THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-12-18 US claimed
US-20240175141-A1 BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION ZestBio, Inc. 2024-05-30 US disclosed
WO-2024081967-A2 BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION ZestBio, Inc. (US) 2024-04-18 WO disclosed
WO-2023213211-A9 2,4-DISUBSTITUTED-5-FLUOROPYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF 长沙晶易医药科技股份有限公司 2024-03-21 WO disclosed
US-4585581-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US disclosed
US-4585581-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US disclosed
US-4488943-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity and methods for manufacturing such blends THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-12-18 US disclosed
US-4488943-A Polymer blends for use in photoelectrochemical cells for conversion of solar energy to electricity and methods for manufacturing such blends THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines HCN2, RAC2, HCN1 SCN2A 546/4885ALDH1A1 1225/4885MAPT 3456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.