SCHEMBL2240222

SCHEMBL2240222

NC1Cc2cccc3cccc1c23

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.44
MTNR1B P49286 8/20 0.44
HTR2A P28223 1/20 0.43
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
ANPEP P15144 3/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
KDM1A O60341 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516700 1.00 MTNR1A (0.44) MTNR1AMTNR1BHTR2ACYP3A4TSHR
SCHEMBL29516800 1.00 MTNR1A (0.44) MTNR1AMTNR1BHTR2ACYP3A4TSHR
SCHEMBL7887852 1.00 MTNR1A (0.44) MTNR1AMTNR1BHTR2ACYP3A4TSHR
SCHEMBL2244164 1.00 MTNR1A (0.44) MTNR1AMTNR1BHTR2ACYP3A4TSHR
Hydrochloric Acid SCHEMBL10785087 0.98 MTNR1A (0.43) MTNR1AMTNR1BHTR2ACYP3A4TSHR
Hydrochloric Acid SCHEMBL2242431 0.98 MTNR1A (0.43) MTNR1AMTNR1BHTR2ACYP3A4TSHR
Bromide SCHEMBL8715151 0.98 MTNR1A (0.43) MTNR1AMTNR1BHTR2ACYP3A4TSHR
Acetic Acid SCHEMBL9983815 0.88 MTNR1A (0.54) MTNR1AMTNR1B
Acetic Acid SCHEMBL9983822 0.88 MTNR1A (0.54) MTNR1AMTNR1B
SCHEMBL7883609 0.80 ADRA2A (0.49) MTNR1AMTNR1BCYP3A4TSHRANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023101060-A1 QUANTUM DOTS AND METHOD FOR PRODUCING SAME 주식회사 제우스 2023-06-08 WO claimed
CN-107466322-B Mutant transaminases and methods and uses related thereto 豪夫迈·罗氏有限公司 2022-04-15 CN claimed
EP-3283622-B1 MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO HOFFMANN LA ROCHE (CH) 2019-07-03 EP claimed
US-10017749-B2 Mutant transaminases as well as methods and uses relating thereto HOFFMAN-LA ROCHE INC. (US) 2018-07-10 US claimed
CN-108128844-A A kind of Modification of Montmorillonite material and its preparation method and application 郑州源冉生物技术有限公司 2018-06-08 CN claimed
CN-107466322-A Saltant type transaminase and relative method and purposes 豪夫迈·罗氏有限公司 2017-12-12 CN claimed
CN-104353127-B Composite antibacterial material of graphene quantum dot and fibroin, preparation and application 中国科学院上海微系统与信息技术研究所 2017-01-25 CN claimed
US-20160304843-A1 MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO HOFFMANN-LA ROCHE INC. (US) 2016-10-20 US claimed
CN-104557597-A Clean production method of 3-(N,N-di-substituted)aminoacetanilide compounds ZHEJIANG LONGSHENG GROUP CO 2015-04-29 CN claimed
CN-104353127-A Composite antibacterial material of graphene quantum dot and fibroin, preparation and application SHANGHAI INST MICROSYS & INF 2015-02-18 CN claimed
CN-103525952-B Method for removing 2-aminoacetophenone in high fructose corn syrup SHANDONG SCENTS JIANYUAN BIO TECH CO LTD 2014-11-05 CN claimed
CN-103642494-A Preparation method for fluorescence carbon-based quantum dot SHANGHAI INST MICROSYS & INF 2014-03-19 CN claimed
CN-103525952-A Method for removing 2-aminoacetophenone in high fructose corn syrup SHANDONG SCENTS JIANYUAN BIO TECH CO LTD 2014-01-22 CN claimed
CN-101281366-A Light-sensitive polymer composition not easy to change color and application thereof MURAKAMI KUNSHAN PREC STENCIL (CN) 2008-10-08 CN claimed
CN-101281370-A Photosensitive resin composition with low surface adhesion and application thereof MURAKAMI KUNSHAN PREC STENCIL (CN) 2008-10-08 CN claimed
CN-1012959-B PROCESS FOR PREPARATION OF BENZODIAZEPINE TROPONIVERKE GMBH & CO KG KOEL (DE) 1991-06-26 CN claimed
EP-0179631-B1 N6-ACENAPHTHYL ADENOSINES AND ANALOGS THEREOF WARNER-LAMBERT COMPANY (US) 1989-04-26 EP claimed
EP-0179631-A2 N6-acenaphthyl adenosines and analogs thereof WARNER-LAMBERT COMPANY (US) 1986-04-30 EP claimed
WO-2023101060-A1 QUANTUM DOTS AND METHOD FOR PRODUCING SAME 주식회사 제우스 2023-06-08 WO disclosed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017749-B2 Mutant transaminases as well as methods and uses relating thereto GOT1, GOT2, OAT MTNR1A 3655/4885MTNR1B 3823/4885HTR2A 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.