SCHEMBL22409166

SCHEMBL22409166

C=C(C)c1ccc(N)nn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
NNMT P40261 1/20 0.31
BCAT2 O15382 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17150526 0.81 BCAT2 (0.38) BCAT2
SCHEMBL5302622 0.77 KCNJ1 (0.43) LMNANNMTBCAT2
SCHEMBL26828742 0.74 APLNR (0.35)
SCHEMBL9924106 0.73 JUN (0.37) LMNA
SCHEMBL28877834 0.72 CYP1A2 (0.33) LMNA
SCHEMBL17814823 0.71
SCHEMBL31490392 0.71
SCHEMBL1255843 0.71
SCHEMBL2177672 0.70 GABRP (0.43) LMNANNMTBCAT2
SCHEMBL21936458 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed
US-20240360120-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. 2024-10-31 US disclosed
EP-3938358-B1 RAD51 INHIBITORS CYTEIR THERAPEUTICS INC (US) 2024-10-02 EP disclosed
CN-114072390-B RAD51 inhibitors 赛泰尔治疗公司 2024-06-11 CN disclosed
US-11932636-B2 RAD51 inhibitors CYTEIR THERAPEUTICS, INC. (US) 2024-03-19 US disclosed
US-20220259198-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. 2022-08-18 US disclosed
CN-114072390-A RAD51 inhibitors 赛泰尔治疗公司 2022-02-18 CN disclosed
US-11247988-B2 RAD51 inhibitors CYTEIR THERAPEUTICS, INC. (US) 2022-02-15 US disclosed
US-11247988-B2 RAD51 inhibitors CYTEIR THERAPEUTICS, INC. (US) 2022-02-15 US disclosed
EP-3938358-A1 RAD51 INHIBITORS Cyteir Therapeutics, Inc. (US) 2022-01-19 EP disclosed
US-20200291014-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. 2020-09-17 US disclosed
US-20200291014-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. 2020-09-17 US disclosed
WO-2020186006-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. (US) 2020-09-17 WO disclosed
WO-2020186006-A1 RAD51 INHIBITORS CYTEIR THERAPEUTICS, INC. (US) 2020-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11247988-B2 RAD51 inhibitors RAD51, MRE11, RAD54L LMNA 2555/4885NNMT 1638/4885BCAT2 3454/4885
US-20220259198-A1 RAD51 INHIBITORS RAD51, MRE11, RAD54L LMNA 2555/4885NNMT 1638/4885BCAT2 3454/4885
US-20200291014-A1 RAD51 INHIBITORS RAD51, MRE11, RAD54L LMNA 2555/4885NNMT 1638/4885BCAT2 3454/4885
US-20240360120-A1 RAD51 INHIBITORS RAD51, MRE11, RAD54L LMNA 2555/4885NNMT 1638/4885BCAT2 3454/4885
US-11932636-B2 RAD51 inhibitors RAD51, MRE11, RAD54L LMNA 2555/4885NNMT 1638/4885BCAT2 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.