Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 4/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22409404 | 1.00 | MTNR1A (0.39) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409436 | 0.90 | BCL2L1 (0.38) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409437 | 0.90 | BCL2L1 (0.38) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409442 | 0.88 | ALDH1A1 (0.39) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409444 | 0.88 | ALDH1A1 (0.39) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409469 | 0.82 | HTR4 (0.39) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409468 | 0.82 | HTR4 (0.39) | MTNR1AMTNR1BBCL2L1KDM4EALDH1A1 | |
| SCHEMBL22409465 | 0.80 | SIGMAR1 (0.39) | BCL2L1KDM4EALDH1A1 | |
| SCHEMBL21523434 | 0.78 | HSD17B10 (0.54) | BCL2L1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL21523433 | 0.78 | HSD17B10 (0.54) | BCL2L1KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111259-B2 | Acylsulfonamide derivatives for treating senescence-associated diseases and disorders | UNITY BIOTECHNOLOGY, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200291050-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11111259-B2 | Acylsulfonamide derivatives for treating senescence-associated diseases and disorders | ACAT1, ARSA, GLA | MTNR1A 1154/4885MTNR1B 1097/4885BCL2L1 3463/4885 |
| US-20200291050-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | ACAT1, ARSA, GLA | MTNR1A 1154/4885MTNR1B 1097/4885BCL2L1 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.