Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318237 | 0.77 | LMNA (0.37) | S1PR2ALDH1A1LMNA | |
| SCHEMBL985142 | 0.75 | KMO (0.39) | S1PR2SMN1; SMN2GPR35ALDH1A1MAPT | |
| SCHEMBL5683134 | 0.74 | LMNA (0.50) | S1PR2SMN1; SMN2GPR35ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11087162 | 0.71 | GABRA1 (0.34) | LMNA | |
| SCHEMBL22418688 | 0.70 | S1PR2 (0.33) | S1PR2HCAR2SMN1; SMN2GPR35ALDH1A1 | |
| SCHEMBL5850051 | 0.70 | POLB (0.45) | S1PR2SMN1; SMN2GPR35ALDH1A1MAPT | |
| SCHEMBL10167708 | 0.70 | NOS3 (0.38) | ALDH1A1LMNA | |
| SCHEMBL7233011 | 0.70 | S1PR2 (0.39) | S1PR2SMN1; SMN2GPR35ALDH1A1MAPT | |
| SCHEMBL1586144 | 0.70 | LMNA (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5321863 | 0.69 | SMN1; SMN2 (0.40) | S1PR2SMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330009-B | Azacyclic compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113330009-A | Nitrogen heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |