SCHEMBL2242587

SCHEMBL2242587

CO[Si](C)(OC)C(C)c1cccc(C(C)[Si](C)(OC)OC)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
FAAH O00519 3/20 0.32
PTGS1 P23219 2/20 0.32
PTGS2 P35354 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MDM4 O15151 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
TYR P14679 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CA5A P35218 1/20 0.31
HTT P42858 1/20 0.31
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3084097 0.86 FAAH (0.38) FAAHKDM4EALDH1A1
SCHEMBL2239550 0.83 ESR1 (0.35)
SCHEMBL1271192 0.82 TP53 (0.43) HDAC4HDAC8PTGS2ALDH1A1TP53
SCHEMBL574711 0.79 HDAC4 (0.38) HDAC4HDAC8PTGS1PTGS2KDM4E
SCHEMBL2242166 0.78 CASR (0.32) MAPTCASR
SCHEMBL3191517 0.76 CHRNA7 (0.37) ALDH1A1MAPTSMN1; SMN2TDP1
SCHEMBL960017 0.74 GABRA1 (0.39) FAAHPTGS1KDM4EALDH1A1CA1
SCHEMBL2242162 0.74
SCHEMBL2887574 0.71 HDAC4 (0.33) HDAC4HDAC8
SCHEMBL2883850 0.71 HDAC4 (0.33) HDAC4HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN claimed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN disclosed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN disclosed
CN-110536932-B Polyorganosiloxane-containing rubber latex, process for producing the same, and polyorganosiloxane-containing rubber graft polymer 三菱化学株式会社 2022-12-23 CN disclosed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN disclosed
EP-3626780-A1 POLYORGANOSILOXANE-CONTAINING-RUBBER LATEX AND PRODUCTION METHOD THEREFOR, POLYORGANOSILOXANE-CONTAINING-RUBBER-GRAFTED POLYMER, POWDER, RESIN COMPOSITION, AND MOLDED OBJECT Mitsubishi Chemical Corporation (JP) 2020-03-25 EP disclosed
US-20200062946-A1 POLYORGANOSILOXANE-CONTAINING-RUBBER LATEX AND PRODUCTION METHOD THEREFOR, POLYORGANOSILOXANE-CONTAINING-RUBBER-GRAFTED POLYMER, POWDER, RESIN COMPOSITION, AND MOLDED OBJECT MITSUBISHI CHEMICAL CORPORATION (JP) 2020-02-27 US disclosed
EP-1719787-B1 GRAFT COPOLYMER, FLAME RETARDANT COMPOSED OF SUCH COPOLYMER AND RESIN COMPOSITION CONTAINING SUCH FLAME RETARDANT KANEKA CORP (JP) 2018-04-04 EP disclosed
US-8541103-B2 Silicone polymer particle and silicone composition containing same KANEKA CORPORATION (JP) 2013-09-24 US disclosed
EP-1777265-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2007-04-25 EP disclosed
EP-1757630-A1 GRAFT COPOLYMER AND RESIN COMPOSITIONS CONTAINING THE SAME Kaneka Corporation (JP) 2007-02-28 EP disclosed
EP-1719787-A1 GRAFT COPOLYMER, FLAME RETARDANT COMPOSED OF SUCH COPOLYMER AND RESIN COMPOSITION CONTAINING SUCH FLAME RETARDANT Kaneka Corporation (JP) 2006-11-08 EP disclosed
US-20060211796-A1 Polyester resin composition KANEKA CORPORATION (JP) 2006-09-21 US disclosed
US-20060183858-A1 Acrylic elastomer composition KANEKA CORPORATION (JP) 2006-08-17 US disclosed
US-20060135692-A1 Rubber-modified styrene resin composition KANEKA CORPORATION (JP) 2006-06-22 US disclosed
EP-1634923-A1 RUBBER-MODIFIED STYRENE RESIN COMPOSITION KANEKA CORPORATION (JP) 2006-03-15 EP disclosed
EP-1614700-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITIONS CONTAINING THE SAME AND PROCESS FOR PRODUCTION OF POLYORGANOSILOXANE EMULSIONS KANEKA CORPORATION (JP) 2006-01-11 EP disclosed
EP-1614715-A1 POLYESTER RESIN COMPOSITION KANEKA CORPORATION (JP) 2006-01-11 EP disclosed