SCHEMBL2242162

SCHEMBL2242162

COC(OC)[SiH2]CCc1cccc(C(C)[Si](C)(OC)OC)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2244712 0.85
SCHEMBL2246130 0.81 TAAR1 (0.38)
SCHEMBL2242171 0.81 CASR (0.31)
SCHEMBL2242166 0.77 CASR (0.32)
SCHEMBL10612702 0.74 MAOB (0.49)
SCHEMBL2242587 0.74 HDAC4 (0.37)
SCHEMBL5076208 0.72 ALDH1A1 (0.38)
SCHEMBL163506 0.70 TAAR1 (0.34)
SCHEMBL3084097 0.67 FAAH (0.38)
SCHEMBL8961186 0.66 LOXL2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210347981-A1 POLYORGANOSILOXANE-CONTAINING-RUBBER LATEX AND PRODUCTION METHOD THEREFOR, POLYORGANOSILOXANE-CONTAINING-RUBBER-GRAFTED POLYMER, POWDER, RESIN COMPOSITION, AND MOLDED OBJECT MITSUBISHI CHEMICAL CORPORATION (JP) 2021-11-11 US disclosed
EP-3626780-A1 POLYORGANOSILOXANE-CONTAINING-RUBBER LATEX AND PRODUCTION METHOD THEREFOR, POLYORGANOSILOXANE-CONTAINING-RUBBER-GRAFTED POLYMER, POWDER, RESIN COMPOSITION, AND MOLDED OBJECT Mitsubishi Chemical Corporation (JP) 2020-03-25 EP disclosed
US-20200062946-A1 POLYORGANOSILOXANE-CONTAINING-RUBBER LATEX AND PRODUCTION METHOD THEREFOR, POLYORGANOSILOXANE-CONTAINING-RUBBER-GRAFTED POLYMER, POWDER, RESIN COMPOSITION, AND MOLDED OBJECT MITSUBISHI CHEMICAL CORPORATION (JP) 2020-02-27 US disclosed
EP-1719787-B1 GRAFT COPOLYMER, FLAME RETARDANT COMPOSED OF SUCH COPOLYMER AND RESIN COMPOSITION CONTAINING SUCH FLAME RETARDANT KANEKA CORP (JP) 2018-04-04 EP disclosed
US-8541103-B2 Silicone polymer particle and silicone composition containing same KANEKA CORPORATION (JP) 2013-09-24 US disclosed
US-7994255-B2 Polyorganiosiloxane-containing graft copolymer, resin compositions containing the same and process for produciton of polyorganosiloxane emulsions KANEKA CORPORATION (JP) 2011-08-09 US disclosed
US-7776966-B2 Thermoplastic resin composition KANEKA CORPORATION (JP) 2010-08-17 US disclosed
US-7705089-B2 Rubber-modified styrene resin composition KANEKA CORPORATION (JP) 2010-04-27 US disclosed
US-20090054591-A1 Polyorganosiloxane-containing graft copolymer and vinyl chloride resin compositions containing the copolymer KANEKA CORPORATION (JP) 2009-02-26 US disclosed
US-20080319140-A1 Thermoplastic Resin Composition KANEKA CORPORATION (JP) 2008-12-25 US disclosed
US-20070225439-A1 Graft Copolymer and Resin Composition Containing the Same KANEKA CORPORATION (JP) 2007-09-27 US disclosed
US-20070167567-A1 Graft copolymer, flame retardant composed of graft copolymer, and resin composition containing flame retardant KANEKA CORPORATION (JP) 2007-07-19 US disclosed
US-20070112157-A1 Polyorganiosiloxane-containing graft copolymer, resin compositions containing the same and process for produciton of polyorganosiloxane emulsions KANEKA CORPORATION (JP) 2007-05-17 US disclosed
EP-1777265-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2007-04-25 EP disclosed
EP-1757630-A1 GRAFT COPOLYMER AND RESIN COMPOSITIONS CONTAINING THE SAME Kaneka Corporation (JP) 2007-02-28 EP disclosed
EP-1719787-A1 GRAFT COPOLYMER, FLAME RETARDANT COMPOSED OF SUCH COPOLYMER AND RESIN COMPOSITION CONTAINING SUCH FLAME RETARDANT Kaneka Corporation (JP) 2006-11-08 EP disclosed
US-20060211796-A1 Polyester resin composition KANEKA CORPORATION (JP) 2006-09-21 US disclosed
US-20060183858-A1 Acrylic elastomer composition KANEKA CORPORATION (JP) 2006-08-17 US disclosed
US-20060135692-A1 Rubber-modified styrene resin composition KANEKA CORPORATION (JP) 2006-06-22 US disclosed
EP-1634923-A1 RUBBER-MODIFIED STYRENE RESIN COMPOSITION KANEKA CORPORATION (JP) 2006-03-15 EP disclosed