Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465263 | 0.88 | ALDH1A1 (0.54) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL27989815 | 0.87 | CYP2A6 (0.74) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL2125063 | 0.81 | CYP2A6 (0.72) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL29161355 | 0.79 | BACE1 (0.60) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL24106775 | 0.77 | CYP2A6 (0.95) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL3997707 | 0.76 | — | — | |
| SCHEMBL4693782 | 0.75 | CYP2A6 (0.58) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL6295431 | 0.75 | CYP2A6 (0.58) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL24164402 | 0.75 | CYP2A6 (0.58) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 | |
| SCHEMBL1310381 | 0.75 | CYP2A6 (0.58) | KCNH2CYP2A6CYP2B6CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117509675-B | Iron-based Prussian blue with low crystal water content, and preparation method and application thereof | 武汉中科先进材料科技有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117509675-A | Iron-based Prussian blue with low crystal water content, and preparation method and application thereof | 武汉中科先进材料科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-101356173-A | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH (DE) | 2009-01-28 | — | — | CN | claimed |
| EP-1957487-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | claimed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | claimed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | claimed |
| EP-4741383-A1 | COMPOUND AND USE THEREOF AS ANTI-CANCER DRUG | Tyligand Bioscience (Shanghai) Limited (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-02-24 | — | — | US | disclosed |
| WO-2025011480-A1 | COMPOUND AND USE THEREOF AS ANTI-CANCER DRUG | 泰励生物科技（上海）有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-117509675-B | Iron-based Prussian blue with low crystal water content, and preparation method and application thereof | 武汉中科先进材料科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117509675-A | Iron-based Prussian blue with low crystal water content, and preparation method and application thereof | 武汉中科先进材料科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11708450-B2 | Composition for forming metallic luster film, metallic luster film, and article | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2023-07-25 | — | — | US | disclosed |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-06-08 | — | — | US | disclosed |
| US-20080015192-A1 | INHIBITORS OF POLO-LIKE KINASES | ABBVIE INC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007140233-A1 | INHIBITORS OF POLO-LIKE KINASES | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | disclosed |
| US-20060229295-A1 | Amide derivatives | ASTELLAS PHARMA INC.AND RATIONAL DRUG DESIGN (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1652843-A1 | AMIDE DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | KCNH2 1766/4885CYP2A6 3336/4885CYP2B6 2536/4885 |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | KCNH2 2919/4885CYP2A6 527/4885CYP2B6 371/4885 |
| US-20060229295-A1 | Amide derivatives | VAC14, HDAC8, ZC3HAV1 | KCNH2 779/4885CYP2A6 3506/4885CYP2B6 3965/4885 |
| US-20080015192-A1 | INHIBITORS OF POLO-LIKE KINASES | PLK1, PLK2, BUB1B | KCNH2 4016/4885CYP2A6 4686/4885CYP2B6 4719/4885 |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | WNT1, CTNND1, WNT3A | KCNH2 692/4885CYP2A6 896/4885CYP2B6 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.