Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781456 | 0.92 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL397259 | 0.88 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL30839749 | 0.83 | CYP3A4 (0.72) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL2206282 | 0.83 | CYP3A4 (0.72) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL3786568 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL31607635 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL31607679 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA | |
| SCHEMBL169281 | 0.83 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1CYP3A4TSHRHSD17B10 | |
| SCHEMBL31607672 | 0.83 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1CYP3A4TSHRHSD17B10 | |
| SCHEMBL7647167 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370965-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-28 | — | — | US | disclosed |
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TST, MT-ND5, MT-ND4L | ALDH1A1 1208/4885L3MBTL1 2087/4885CYP3A4 3492/4885 |
| US-11370965-B2 | Materials for organic electroluminescent devices | TST, MT-ND5, MT-ND4L | ALDH1A1 1208/4885L3MBTL1 2087/4885CYP3A4 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.