Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966426 | 1.00 | LMNA (0.44) | LMNAS1PR2SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL22966357 | 0.98 | SMN1; SMN2 (0.42) | LMNAS1PR2SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL20309049 | 0.88 | LMNA (0.43) | LMNAS1PR2SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL19565806 | 0.88 | LMNA (0.43) | LMNAS1PR2SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL25680427 | 0.87 | LOXL2 (0.46) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL25679947 | 0.81 | LOXL2 (0.43) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL14532288 | 0.80 | LOXL2 (0.48) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL20856477 | 0.78 | HTR1A (0.54) | LMNAS1PR2SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL20244030 | 0.78 | LOXL2 (0.43) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL25113038 | 0.77 | KDM4E (0.40) | LMNAS1PR2SMN1; SMN2NPSR1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038749-A1 | FAP INHIBITOR | Universität Heidelberg (DE) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038749-A1 | FAP INHIBITOR | FAP, APC, FIBP | LMNA 1644/4885S1PR2 3454/4885SMN1; SMN2 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.