Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 8/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.59 |
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243866 | 0.88 | C3AR1 (0.67) | C3AR1SUCNR1BMP1PRSS1TMPRSS15 | |
| SCHEMBL2247803 | 0.84 | C3AR1 (0.55) | C3AR1SUCNR1 | |
| SCHEMBL2246549 | 0.82 | RXRA (0.58) | C3AR1PRSS1 | |
| SCHEMBL2245141 | 0.81 | C3AR1 (0.61) | C3AR1SUCNR1SLC9A1 | |
| SCHEMBL3581169 | 0.80 | C3AR1 (0.57) | C3AR1SUCNR1BMP1 | |
| SCHEMBL2247341 | 0.80 | C3AR1 (0.53) | C3AR1SUCNR1 | |
| SCHEMBL18252676 | 0.77 | C3AR1 (0.57) | C3AR1SUCNR1BMP1SLC9A1 | |
| SCHEMBL26263253 | 0.76 | SUCNR1 (0.83) | C3AR1SUCNR1 | |
| SCHEMBL26264369 | 0.75 | SUCNR1 (1.00) | C3AR1SUCNR1PRSS1TMPRSS15 | |
| SCHEMBL2246916 | 0.74 | CA2 (0.58) | SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998965-B2 | Glutamate aggrecanase inhibitors | WYETH LLC (US) | 2011-08-16 | — | — | US | disclosed |