Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 13/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247335 | 0.86 | C3AR1 (0.46) | C3AR1SUCNR1 | |
| SCHEMBL2247803 | 0.85 | C3AR1 (0.55) | C3AR1CA2CA1KMT2ASUCNR1 | |
| SCHEMBL2247532 | 0.80 | CA2 (0.58) | C3AR1CA2CA1KMT2A | |
| SCHEMBL2243871 | 0.80 | C3AR1 (0.75) | C3AR1SUCNR1 | |
| SCHEMBL2244829 | 0.80 | S1PR4 (0.48) | C3AR1CA2CA1KMT2AALDH1A1 | |
| SCHEMBL2245141 | 0.78 | C3AR1 (0.61) | C3AR1CA2CA1KMT2ASUCNR1 | |
| SCHEMBL2248654 | 0.78 | TAS1R3 (0.53) | C3AR1CA2CA1KMT2AALDH1A1 | |
| SCHEMBL3578207 | 0.77 | MMP2 (0.46) | CA2CA1KMT2AALDH1A1 | |
| SCHEMBL4621088 | 0.75 | C3AR1 (0.46) | C3AR1SUCNR1ALDH1A1 | |
| SCHEMBL10571826 | 0.73 | NAALAD2 (0.57) | CA2CA1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998965-B2 | Glutamate aggrecanase inhibitors | WYETH LLC (US) | 2011-08-16 | — | — | US | disclosed |