Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448159 | 0.88 | LTA4H (0.40) | TBK1SLC5A1SLC5A2TRPV3 | |
| SCHEMBL22448157 | 0.85 | TRPV3 (0.34) | TBK1SLC5A1SLC5A2TRPV3HDAC4 | |
| SCHEMBL22448141 | 0.84 | TAAR1 (0.33) | TBK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22570525 | 0.83 | LTA4H (0.44) | SLC5A1SLC5A2 | |
| SCHEMBL24945601 | 0.78 | TRPV3 (0.36) | TBK1SLC5A1SLC5A2TRPV3HDAC4 | |
| SCHEMBL30407818 | 0.74 | SIGMAR1 (0.39) | HSD11B1FFAR2TBK1TRPV3HDAC4 | |
| SCHEMBL8093837 | 0.72 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28815014 | 0.70 | SLC13A5 (0.36) | FFAR2TBK1HDAC4 | |
| SCHEMBL22448205 | 0.68 | LTA4H (0.38) | TBK1SLC5A1SLC5A2 | |
| SCHEMBL21427484 | 0.68 | HTR2C (0.43) | FFAR2TBK1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712147-B1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021004388-A1 | CRYSTAL FORM OF SGLT INHIBITOR AND APPLICATION THEREOF | 山东丹红制药有限公司 | 2021-01-14 | — | — | WO | disclosed |
| US-10822365-B1 | SGLTS inhibitor and application thereof | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2020-11-03 | — | — | US | disclosed |
| US-20200331950-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-10-22 | — | — | US | disclosed |
| EP-3712147-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | Shangdong Danhong Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822365-B1 | SGLTS inhibitor and application thereof | SLC5A1, SLC5A2, SLC5A11 | HSD11B1 155/4885FFAR2 793/4885TBK1 3049/4885 |
| US-20200331950-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SLC5A1, SLC5A2, SLC5A11 | HSD11B1 155/4885FFAR2 793/4885TBK1 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.