Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086923 | 0.93 | CALM1 (0.55) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL6548117 | 0.92 | HTR2A (0.56) | HTR2ATSHRTP53CALM1LMNA | |
| SCHEMBL8095786 | 0.91 | LTA4H (0.46) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL6547993 | 0.91 | POLB (0.45) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL11205678 | 0.90 | HTR2A (0.54) | HTR2AGABRA1GABRB2TP53CALM1 | |
| SCHEMBL27473436 | 0.89 | LMNA (0.44) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL11299196 | 0.89 | SLC6A2 (0.44) | SLC6A4SLC6A2SLC6A3TP53LMNA | |
| SCHEMBL7789726 | 0.87 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL9418577 | 0.87 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3HTR2AKEAP1 | |
| SCHEMBL11205375 | 0.86 | GABRA1 (0.57) | GABRA1GABRB2TP53LMNAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |