Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448159 | 0.85 | LTA4H (0.40) | TAAR1HTR2CHTR2BTBK1 | |
| SCHEMBL22448157 | 0.85 | TRPV3 (0.34) | TAAR1HTR2CHTR2BTBK1 | |
| SCHEMBL22448133 | 0.84 | HSD11B1 (0.33) | SLC6A2SLC6A4SLC6A3TBK1 | |
| SCHEMBL22570525 | 0.81 | LTA4H (0.44) | HTR2CL3MBTL1IDO1 | |
| SCHEMBL30407818 | 0.74 | SIGMAR1 (0.39) | HTR2CL3MBTL1SIGMAR1TBK1 | |
| SCHEMBL8752818 | 0.70 | SMN1; SMN2 (0.47) | TAAR1L3MBTL1SIGMAR1PNMTIDO1 | |
| SCHEMBL21427484 | 0.68 | HTR2C (0.43) | HTR2CSIGMAR1TBK1 | |
| SCHEMBL28815014 | 0.68 | SLC13A5 (0.36) | TBK1 | |
| SCHEMBL2089904 | 0.67 | KDM4E (0.53) | TAAR1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL3814505 | 0.67 | MEN1 (0.50) | TAAR1SLC6A2SLC6A4SLC6A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712147-B1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |
| EP-3712147-A1 | SGLTS INHIBITOR AND APPLICATION THEREOF | Shangdong Danhong Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |