⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345852 | 0.76 | LMNA (0.37) | — | |
| SCHEMBL29348245 | 0.75 | OPRM1 (0.30) | — | |
| SCHEMBL22511149 | 0.69 | SIGMAR1 (0.36) | — | |
| SCHEMBL12228048 | 0.69 | CRBN (0.35) | — | |
| SCHEMBL22511151 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL24851905 | 0.65 | — | — | |
| SCHEMBL22450108 | 0.65 | KDM4E (0.32) | — | |
| SCHEMBL13003405 | 0.65 | DDB1 (0.44) | — | |
| SCHEMBL12612290 | 0.64 | BRD4 (0.37) | — | |
| SCHEMBL15974005 | 0.64 | KMT2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847096-B2 | 4-aminophenylmorpholinone derivatives and their preparation | SALTIGO GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| US-20090018126-A1 | 4-Aminophenylmorpholinone Derivatives and Their Preparation | SALTIGO GMBH (DE) | 2009-01-15 | — | — | US | disclosed |