Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | MDH1 | P40925 | 2/20 | 0.36 |
| ▸ | MDH2 | P40926 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453036 | 0.91 | HIF1A (0.36) | HIF1AEPAS1LTC4SCASP2KMT2A | |
| SCHEMBL22452675 | 0.89 | MDH1 (0.39) | CNR2HIF1AEPAS1MDH1MDH2 | |
| SCHEMBL22452627 | 0.87 | CNR2 (0.51) | CNR2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22452666 | 0.87 | CNR2 (0.43) | CNR2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22453410 | 0.87 | CNR2 (0.46) | CNR2HIF1AEPAS1MDH1MDH2 | |
| SCHEMBL22452628 | 0.87 | CNR2 (0.47) | CNR2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22453558 | 0.84 | CNR2 (0.47) | CNR2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22453152 | 0.84 | CNR2 (0.47) | CNR2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22453418 | 0.81 | TAS2R14 (0.41) | HIF1AEPAS1MDH1MDH2KMT2A | |
| SCHEMBL22452973 | 0.81 | CNR2 (0.40) | CNR2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |