Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | NR0B2 | Q15466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453360 | 0.88 | HTR2A (0.33) | HTR2CHTR2BPDE7AFFAR1EPHX2 | |
| SCHEMBL22453159 | 0.88 | PDE7A (0.43) | PDE7AFFAR1EPHX2HTR2ASLC6A4 | |
| SCHEMBL22453130 | 0.80 | EPHX2 (0.39) | EPHX2MEN1KMT2APTPN11NR0B2 | |
| SCHEMBL22452986 | 0.78 | AKR1C3 (0.40) | HTR2AKCNH2MEN1NPC1KMT2A | |
| SCHEMBL22453332 | 0.77 | LMNA (0.41) | EPHX2MEN1KMT2A | |
| SCHEMBL22453440 | 0.77 | TOP1 (0.39) | EPHX2MEN1KMT2A | |
| SCHEMBL22453441 | 0.77 | TDP1 (0.37) | EPHX2MEN1KMT2A | |
| SCHEMBL2730836 | 0.77 | EPHX2 (0.34) | EPHX2MEN1KMT2APTPN11NR0B2 | |
| SCHEMBL9332143 | 0.71 | MAPT (0.51) | FFAR1HTR2ASLC6A4KCNH2L3MBTL1 | |
| SCHEMBL22453702 | 0.71 | PTPN11 (0.45) | EPHX2MEN1KMT2APTPN11NR0B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |