Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDH1 | P12830 | 1/20 | 0.45 |
| ▸ | APC | P25054 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355762 | 1.00 | TDP1 (0.48) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL12355830 | 0.93 | TDP1 (0.61) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL1162363 | 0.86 | CDH1 (0.47) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL12355834 | 0.83 | RAB9A (0.40) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL12365622 | 0.83 | RAB9A (0.37) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL2251523 | 0.81 | TDP1 (0.71) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL2251936 | 0.81 | TDP1 (0.71) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL18995950 | 0.78 | TDP1 (0.57) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL5007899 | 0.76 | ALDH1A1 (0.46) | TDP1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL10584287 | 0.76 | ALDH1A1 (0.46) | TDP1CDH1APCCTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994423-B2 | Charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | GEORGIA TECH RESEARCH CORPORATION | 2009-03-12 | — | — | US | disclosed |
| WO-2005123737-A9 | CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | TY OF ARIZONA ARIZONA BOARD OF (US) | 2006-04-06 | — | — | WO | disclosed |
| WO-2005123737-A2 | CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090065057-A1 | Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof | SLC9A3, SLC18A2, SLC9A2 | TDP1 1229/4885CDH1 98/4885APC 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.