Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453501 | 0.96 | KMT2A (0.45) | KMT2ASLC7A5GAANPSR1ABCB1 | |
| SCHEMBL22452884 | 0.88 | KMT2A (0.48) | KMT2AGAANPSR1ALDH1A1MAPT | |
| SCHEMBL4956421 | 0.78 | KMT2A (0.59) | KMT2AGAANPSR1ALDH1A1MAPT | |
| SCHEMBL5608478 | 0.77 | TSHR (0.58) | KMT2AMTNR1AMTNR1BSLC7A5ALDH1A1 | |
| SCHEMBL22453561 | 0.75 | CNR2 (0.53) | KMT2ANPSR1ALDH1A1MAPTKDM4E | |
| SCHEMBL22453460 | 0.75 | KMT2A (0.52) | KMT2AGAANPSR1ALDH1A1MAPT | |
| SCHEMBL11351276 | 0.75 | RORC (0.51) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL10835203 | 0.75 | KMT2A (0.55) | KMT2AGAANPSR1ALDH1A1MAPT | |
| SCHEMBL30740693 | 0.75 | KMT2A (0.55) | KMT2AGAANPSR1ALDH1A1MAPT | |
| SCHEMBL31505051 | 0.73 | TCF4 (0.53) | MTNR1AMTNR1BALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |