Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453449 | 0.86 | HIF1A (0.51) | ALDH1A1KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL22453521 | 0.85 | EPHX2 (0.47) | ALDH1A1KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL22452764 | 0.77 | KMT2A (0.48) | ALDH1A1KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL22452725 | 0.76 | MEN1 (0.46) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL22453772 | 0.75 | MAPT (0.48) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL22452983 | 0.74 | MEN1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL22452498 | 0.73 | HIF1A (0.60) | ALDH1A1KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL31555348 | 0.73 | HIF1A (0.60) | ALDH1A1KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL22453451 | 0.72 | TAS2R14 (0.47) | FABP4AKR1C3AKR1C2 | |
| SCHEMBL22453248 | 0.71 | DHODH (0.49) | ALDH1A1MEN1KMT2AGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |