SCHEMBL22465

SCHEMBL22465

O=C(O)C1(C(=O)O)C=CC(c2ccccc2)=CC1(C(=O)O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.32
MGLL Q99685 1/20 0.32
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
GAA P10253 3/20 0.31
LMNA P02545 2/20 0.31
ABCC4 O15439 1/20 0.31
TSHR P16473 1/20 0.31
PTGS1 P23219 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 2/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17202669 0.85 THRB (0.36) THRBTDP1TP53MGLLMAPT
SCHEMBL20702294 0.85 THRB (0.36) THRBTDP1TP53MGLL
SCHEMBL5848007 0.85 THRB (0.32) THRBTDP1TP53MGLLMEN1
SCHEMBL5847347 0.85 THRB (0.32) THRBTDP1TP53MGLLMEN1
SCHEMBL9680128 0.84 ALDH1A1 (0.34) THRBTDP1TP53MAPTSMN1; SMN2
SCHEMBL28358615 0.84 THRB (0.32) THRBTDP1TP53
SCHEMBL1556026 0.75 POLB (0.35) THRBTDP1ALDH1A1TSHRHTT
SCHEMBL31116925 0.73 THRB (0.40) THRBTDP1SMN1; SMN2ALDH1A1MEN1
SCHEMBL27633772 0.72 THRB (0.34) THRBTDP1
SCHEMBL27629970 0.69 THRB (0.33) THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11868047-B2 Polymer layer in semiconductor device and method of manufacture TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2024-01-09 US claimed
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US claimed
CN-114479079-B Polyimide aerogel and preparation method thereof 军事科学院系统工程研究院军需工程技术研究所 2023-06-27 CN claimed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
CN-111542562-B Method for preparing polyamic acid, polyamic acid prepared by same, polyimide resin and polyimide film 可隆工业株式会社 2023-04-18 CN claimed
CN-115926615-A High-wear-resistance polyimide wire enamel and preparation method thereof 江苏四达特材科技有限公司 2023-04-07 CN claimed
CN-115805063-A Multifunctional porous core-shell composite nano material and preparation method thereof 浙江大学 2023-03-17 CN claimed
CN-115458705-A Carbon-coated aluminum foil with high cohesiveness 鼎圭新材料科技(上海)有限公司 2022-12-09 CN claimed
WO-2022202769-A1 POLY(AMIC ACID), POLY(AMIC ACID) SOLUTION, POLYIMIDE, POLYIMIDE SUBSTRATE AND LAYERED PRODUCT, AND METHODS FOR PRODUCING THESE 株式会社カネカ 2022-09-29 WO claimed
CN-114989466-A Corona-resistant polyimide film and preparation method thereof 潍坊弘润新材料有限公司 2022-09-02 CN claimed
US-20040220377-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US claimed
US-20040176496-A1 Light-curing dental adhesive compositions DENTKIST, INC. (KR) 2004-09-09 US claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
US-6541178-B2 An sulfonium(-) and iodonium(+)ion-type photoacid generator containing a naphthol structure, and photosensitive polyimide resin using photoacid generator SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-04-01 US claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
US-20020048719-A1 Ion-type photoacid generator containing naphthol and photosensitive polyimide composition prepared by using the same SAMSUNG ELECTRONICS CO., LTD. 2002-04-25 US claimed
JP-3261411-B2 2002-03-04 JP claimed
EP-0880555-A1 METHOD OF MAKING FREE-STANDING POLYIMIDE FILM OCCIDENTAL CHEMICAL CORPORATION (US) 1998-12-02 EP claimed
WO-1997018259-A1 METHOD OF MAKING FREE-STANDING POLYIMIDE FILM OCCIDENTAL CHEMICAL CORPORATION (US) 1997-05-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176496-A1 Light-curing dental adhesive compositions HBG2, GRIN2A, HBG1 THRB 1323/4885TDP1 3235/4885TP53 3180/4885
US-20020048719-A1 Ion-type photoacid generator containing naphthol and photosensitive polyimide composition prepared by using the same ASIC1, H1-0, RER1 THRB 3875/4885TDP1 1984/4885TP53 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.