Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.39 |
| ▸ | LPL | P06858 | 6/20 | 0.39 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707007 | 0.89 | F11 (0.34) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL7046117 | 0.81 | F11 (0.31) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1291127 | 0.80 | F11 (0.35) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL28452781 | 0.77 | F11 (0.35) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL27702319 | 0.75 | NOS2 (0.41) | MEN1ALDH1A1KMT2AHSD17B10CXCR5 | |
| SCHEMBL3823509 | 0.74 | CCNC (0.34) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28273750 | 0.73 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2AHSD17B10USP2 | |
| SCHEMBL28507189 | 0.72 | F11 (0.35) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL6601847 | 0.72 | NOS2 (0.39) | MEN1ALDH1A1KMT2AHSD17B10CXCR5 | |
| SCHEMBL5706992 | 0.72 | CDC7 (0.34) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198053-A1 | 2-OXO-2,3-DIHYDRO-1H-IMIDAZO[4,5-B]PYRIDIN-6-YL)-4-METHYLBENZAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS RIPK2 INHIBITORS FOR TREATING E.G. AUTOIMMUNE DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-10-01 | — | — | WO | disclosed |