Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385645 | 0.80 | KDM4E (0.32) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20929171 | 0.77 | KDM4E (0.30) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29350654 | 0.77 | KDM4E (0.30) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25307167 | 0.76 | PKM (0.30) | — | |
| SCHEMBL20865941 | 0.73 | — | — | |
| SCHEMBL16692012 | 0.72 | FGFR2 (0.36) | KDM1AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL31736077 | 0.71 | KDM4E (0.37) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30770093 | 0.70 | — | — | |
| SCHEMBL15274416 | 0.70 | KDM4E (0.32) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2470697 | 0.69 | ALDH1A1 (0.42) | KCNH2KDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275719-B2 | Small molecule inhibitors of galectin-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-15 | — | — | US | disclosed |
| EP-3947407-B1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20220185800-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2022-06-16 | — | — | US | disclosed |
| EP-3947407-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | Bristol-Myers Squibb Company (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113727988-A | Small molecule inhibitors of galectin-3 | 百时美施贵宝公司 | 2021-11-30 | — | — | CN | disclosed |
| WO-2020198266-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198266-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275719-B2 | Small molecule inhibitors of galectin-3 | LGALS3, LGALS1, LGALS3BP | KDM1A 3247/4885KCNH2 3808/4885KDM1B 3360/4885 |
| US-20220185800-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | KDM1A 3247/4885KCNH2 3808/4885KDM1B 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.